Program/TargetProg/Tgt |
IndicationInd |
DiscoveryDiscov |
Lead OptimizationLead Opt |
IND EnablingIND |
Phase 1Ph 1 |
Phase 2Ph 2 |
CollaborationsCollab |
|
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NSCLC |
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NSCLC
|
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Class I HDAC inhibition has been shown to dramatically enhance the efficacy of MEK inhibitors in Ras pathway driven melanomas by coordinately suppressing two DNA repair pathways. A potential clinical biomarker that predicts responsiveness has also been identified.
|
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ER+ Breast Cancer |
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ER+ Breast Cancer
|
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Class I HDAC inhibition has been shown to dramatically enhance the efficacy of MEK inhibitors in Ras pathway driven melanomas by coordinately suppressing two DNA repair pathways. A potential clinical biomarker that predicts responsiveness has also been identified.
|
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Undisclosed |
||||||||
Undisclosed
|
||||||||
Class I HDAC inhibition has been shown to dramatically enhance the efficacy of MEK inhibitors in Ras pathway driven melanomas by coordinately suppressing two DNA repair pathways. A potential clinical biomarker that predicts responsiveness has also been identified.
|
||||||||
Undisclosed |
||||||||
Undisclosed
|
||||||||
Class I HDAC inhibition has been shown to dramatically enhance the efficacy of MEK inhibitors in Ras pathway driven melanomas by coordinately suppressing two DNA repair pathways. A potential clinical biomarker that predicts responsiveness has also been identified.
|
||||||||
Undisclosed |
||||||||
Undisclosed
|
||||||||
Class I HDAC inhibition has been shown to dramatically enhance the efficacy of MEK inhibitors in Ras pathway driven melanomas by coordinately suppressing two DNA repair pathways. A potential clinical biomarker that predicts responsiveness has also been identified.
|
||||||||
Undisclosed |
||||||||
Undisclosed
|
||||||||
Class I HDAC inhibition has been shown to dramatically enhance the efficacy of MEK inhibitors in Ras pathway driven melanomas by coordinately suppressing two DNA repair pathways. A potential clinical biomarker that predicts responsiveness has also been identified.
|