Program/TargetProg/Tgt
IndicationInd
DiscoveryDiscov
Lead
Optimization
Lead Opt
IND
Enabling
IND
Phase 1Ph 1
Phase 2Ph 2
CollaborationsCollab
FWD1509
NSCLC
FWD1509
(EGFR/HER2 Inhibitor)
NSCLC
Class I HDAC inhibition has been shown to dramatically enhance the efficacy of MEK inhibitors in Ras pathway driven melanomas by coordinately suppressing two DNA repair pathways. A potential clinical biomarker that predicts responsiveness has also been identified.
FWD1802
ER+ Breast Cancer
FWD1802
(SERD)
ER+ Breast Cancer
Class I HDAC inhibition has been shown to dramatically enhance the efficacy of MEK inhibitors in Ras pathway driven melanomas by coordinately suppressing two DNA repair pathways. A potential clinical biomarker that predicts responsiveness has also been identified.
FWD-K01
Undisclosed
FWD-K01
(2nd KRAS G12C Inhibitor)
Undisclosed
Class I HDAC inhibition has been shown to dramatically enhance the efficacy of MEK inhibitors in Ras pathway driven melanomas by coordinately suppressing two DNA repair pathways. A potential clinical biomarker that predicts responsiveness has also been identified.
FWD-K02
Undisclosed
FWD-K02
(KRAS G12D Inhibitor)
Undisclosed
Class I HDAC inhibition has been shown to dramatically enhance the efficacy of MEK inhibitors in Ras pathway driven melanomas by coordinately suppressing two DNA repair pathways. A potential clinical biomarker that predicts responsiveness has also been identified.
FWD-F01
Undisclosed
FWD-F01
(Selective FGFR2 Inhibitor)
Undisclosed
Class I HDAC inhibition has been shown to dramatically enhance the efficacy of MEK inhibitors in Ras pathway driven melanomas by coordinately suppressing two DNA repair pathways. A potential clinical biomarker that predicts responsiveness has also been identified.
FWD-H01
Undisclosed
FWD-H01
(I/O Target Inhibitor)
Undisclosed
Class I HDAC inhibition has been shown to dramatically enhance the efficacy of MEK inhibitors in Ras pathway driven melanomas by coordinately suppressing two DNA repair pathways. A potential clinical biomarker that predicts responsiveness has also been identified.